Medical/Science Study World

For patient safety and convenience, biopsies are usually performed on the posterior iliac crest. The biopsy specimen should measure at least 1.6 cm and, if it does not, consideration should be given to repeating the procedure, possibly on the contralateral iliac crest. If bone marrow aspiration is found to be impossible, imprints from the biopsy specimen should be obtained. Otherwise, the specimen is placed immediately into fixative and after fixation is embedded in a resin or, more usually, decalcified and embedded in paraffin wax. Thin sections are cut and are stained, as a minimum, with haematoxylin and eosin and with a reticulin stain Indications for performing a trephine biopsy. It can be: + Inadequate or failed aspirate. + Need for accurate assessment of cellularity, whether increased or decreased. + Suspected focal lesion (for example, suspected granulomatous disease or lymphoma). + Suspected bone marrow fibrosis. + Need to study bone marrow architecture. + Need to

  UNIT 4 BONE MARROW EXAMINATION BONE MARROW: Bone marrow is soft, spongy, gelatinous tissue that fills the centers of bones known as medullary cavities. Bone marrow is highly vascular meaning that it is enriched with blood vessels and capillaries. Each day bone marrow produces hundreds of billions of new blood cells.Inadult humans, bone marrow is primarily located in the ribs, vertebrae, sternum, and bones of the pelvis. Bone marrow comprises approximately 5% of total body mass in healthy adult humans, such that a man weighing 73 kg will have around 3.65 kg of bone marrow. Types of Bone Marrow 1. Red Bone Marrow It is also known as myeloid tissue. Its main function is to produce blood cells. In addition, it also helps to remove old cells from blood circulation (spleen and liver also remove old and damaged blood cells from the blood).From birth to early adolescence, the majority of our bone marrow is red marrow. With

  There are many conditions in the laboratory have the potential for causing injury to staff and damage to the building or to the community. Patients’ specimens, needles, chemicals, electrical equipment, reagents, and glassware all are potential causes of accidents or injury. Managers and employees must be knowledgeable about safe work practices and incorporate these practices into the operation of the hematology laboratory. The key to prevention of accidents and laboratory-acquired infections is a well-defined safety program. 1. Hand-washing is one of the most important safety practices. Hands must be washed with soap and water. If water is not readily available, alcohol hand gels (minimum 62% alcohol) may be used. Hands must be thoroughly dried. The proper technique for handwashing is as follows: a. Wet hands and wrists thoroughly under running water. b. Apply germicidal soap and rub hands vigorously for at least 15 seconds, including between the fingers and around and over the