Investigations of a case suffering from bleeding disorders B l eed i ng D iso r de r s Hemo s t a s i s • H emo s t asis is the ar r e s t of blood fl o w and c o n t r ol of hemorr h a g e f r om an i n ju r ed b l ood v esse l . Th e e n ti r e mechani s m of hemo s t asis c an be d i v i de d i n t o th r ee parts: 1. Ext r a v ascular e f f ec ts 2. V ascular e f f ect s : i. V aso c on s tr i ction: se r o t on i n b y p l asma i i . P l a t el e t P l ug: c ol l a g e n c o n t act with p l a t el e t and p l a t el e t r elease ADP then se r o t on i n and f ac t or 3 part i ci p a t es in c oagul a t i on. 3. I n t r a v ascular e f f ec ts: I n tr i ns i c f ac t or t o f orm a f i br i n clot. When investigating a case of bleeding disorder , the g...