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    https://acutecaretesting.org/en/articles/hemoglobin-and-its-measurement  

  Disseminated intravascular coagulation ( DIC ) is a condition in which blood clots form throughout the body, blocking small blood vessels . Symptoms may include chest pain , shortness of breath , leg pain, problems speaking, or problems moving parts of the body. As clotting factors and platelets are used up, bleeding may occur. This may include blood in the urine , blood in the stool , or bleeding into the skin.Complications may include organ failure . Diagnosis is typically based on blood tests .  Findings may include low platelets , low fibrinogen , high INR , or high D-dimer . Treatment is mainly directed towards the underlying condition. https://www.slideshare.net/girishpulapa/disseminated-intravascular-coagulation-36564315?qid=3081c27b-20d3-4fc6-b92c-2a2a9650e2bf&v=&b=&from_search=5   https://slideplayer.com/slide/4914646/?authuser=0 https://drive.google.com/file/d/1Ps4g7QeCud_VDYZkltd1fi3orHJMnYVT/view . .

In fibrinolysis, a fibrin clot, the product of coagulation , is broken down. Its main enzyme plasmin cuts the fibrin mesh at various places, leading to the production of circulating fragments that are cleared by other proteases or by the kidney and liver .    Mechanism or Physiology  Plasmin is produced in an inactive form, plasminogen , in the liver. Although plasminogen cannot cleave fibrin, it still has an affinity for it, and is incorporated into the clot when it is formed. Tissue plasminogen activator (t-PA) and urokinase are the agents that convert plasminogen to the active plasmin, thus allowing fibrinolysis to occur. t-PA is released into the blood slowly by the damaged endothelium of the blood vessels, such that, after several days (when the bleeding has stopped), the clot is broken down. This occurs because plasminogen became entrapped within the clot when it formed; as it is slowly activated, it breaks down the fibrin mesh. t-PA and urokinase are themselves

  Park’s Textbook of preventive and social medicine 25th edition The Park’s Textbook of preventive and social  medicine  is a book of PSM (Community Medicine) that is used by the medical students in their course. The detailed and lengthy book does haunt for sometimes, but then medicos get used to it. We have provided the links to the K Park Textbook of Preventive and Social Medicine eBook in PDF Format for free download below. The book is must read for community medicine during the study since it is the most widely used book by medical students. The Epidemiology, Screening for disease, Epidemiology of communicable diseases and chronic non-communicable diseases are usually focused on the exams. Key Faetures : The Index starts with 22 Sections each featuring the chapters, in total in over 942 pages. The book is more closely related to medicine and is must read if you want to establish your base for medicine in the fourth year of mbbs. You will realize you have actually studied most of it