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Clinical Pathology Notes (BSOT408-19)

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Clinical Haematology Notes (BSOT407-19)

Clinical Hematology  1. Introduction to Hematology : (a) Definition (b) Importance 2. Introduction to blood,       its composition,        function        and        normal cellular components. 3. Collection and preservation of blood sample for various haematological investigations. 4. Definition, Normal values, Clinical significance, understanding errors involved for the following” (a) Haemoglobinometry (b) Total leucocytes count (TLC) (c) Differential leucocytes count (DLC) (d) Erythrocyte Sedimentation Rate (ESR) (e) Packed cell volume/ Haematocrit value. (f) Red cell Indices (RCI) (g) Absolute Eosinophil count (h) Reticulocyte count (i) Platelet Count. 5. CBC reading and interpretation 6. Trauma & Bleeding Disorders including DIC 7. To understand importance coagulation studies and commonly used parameters like bleeding time, prothrombin time etc. 8. Shock : Hemorrhagic & Hypovolemic 9. Brief Know...
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Laboratory diagnosis of Leukemoid Reaction

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Sample Blood in   EDTA   is needed along with fresh blood smear. Definition The term leukemoid reaction describes an increased white blood cell count (< 50,000 cells/μL), which is a physiological response to stress or infection (as opposed to a primary blood malignancy, such as leukemia). It often describes the presence of immature cells such as myeloblasts or red blood cells with nuclei in the peripheral blood. It may be   lymphoid   or   myeloid . If there is a persistent increase in the neutrophils, reactive and excessive leucocytosis with a count of 30,000 to 50,000 / µL, with the presence of immature and mature white cells in the peripheral blood smear is called Leukemoid reaction. Sometimes lymphocytic reaction maybe seen. This is not primary marrow disorder, and this is due to the secondary to infections.   Significance This term is used to differentiate between the leucocytosis and leukemia. In leukocytosis or neutrophilia there is an increase in...
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